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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMBRA1 All Species: 15.15
Human Site: Y734 Identified Species: 41.67
UniProt: Q9C0C7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C7 NP_060219.2 1298 142507 Y734 Y A Q R M I Q Y L S R R D S I
Chimpanzee Pan troglodytes XP_001163113 1208 132805 Q659 R Q R S M R Y Q Q N R L R S S
Rhesus Macaque Macaca mulatta XP_001112256 1298 142465 Y734 Y A Q R M I Q Y L S R R D S I
Dog Lupus familis XP_540754 1211 132916 R662 S M R Y Q Q N R L R S S T S S
Cat Felis silvestris
Mouse Mus musculus A2AH22 1300 142860 Y735 Y A Q R M I Q Y L S R R D S I
Rat Rattus norvegicus NP_001127813 1300 142989 Y735 Y A Q R M I Q Y L S R R D S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233289 1300 142720 L737 A Q R M I Q Y L S R R D S I R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342016 1003 110813 Q454 Q P G P S H Y Q S P Y S G E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797133 781 86047 Y232 T L E Q A R E Y A A S V T L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.9 99 89.8 N.A. 95.6 95.9 N.A. N.A. 83 N.A. 47.6 N.A. N.A. N.A. N.A. 27.6
Protein Similarity: 100 93 99.3 90.7 N.A. 97.1 97.3 N.A. N.A. 88.9 N.A. 58.7 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 20 100 13.3 N.A. 100 100 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 33.3 100 20 N.A. 100 100 N.A. N.A. 20 N.A. 0 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 45 0 0 12 0 0 0 12 12 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 45 0 0 % D
% Glu: 0 0 12 0 0 0 12 0 0 0 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 45 0 0 0 0 0 0 0 12 45 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 0 0 0 0 12 56 0 0 12 0 12 0 % L
% Met: 0 12 0 12 56 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 12 0 0 0 0 23 % N
% Pro: 0 12 0 12 0 0 0 0 0 12 0 0 0 0 0 % P
% Gln: 12 23 45 12 12 23 45 23 12 0 0 0 0 0 0 % Q
% Arg: 12 0 34 45 0 23 0 12 0 23 67 45 12 0 12 % R
% Ser: 12 0 0 12 12 0 0 0 23 45 23 23 12 67 23 % S
% Thr: 12 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 45 0 0 12 0 0 34 56 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _